This suggested route begins in Mainz, home to the impressive Mainz Cathedral and the Gutenberg Museum, named after the inventor, Johannes Gutenberg. You’ll pass through Speyer, a city of wonders, and a brief journey leads to the renowned German Wine Road. Picture this: rolling hills dotted with vineyards, picturesque villages, and exceptional wine. The route from Speyer to Wissembourg is a multisensory experience, crossing into France and leading to the enchanting city of Strasbourg—a true melting pot of German and French cultures.
Embark on the Alsace Wine Route, which weaves its way through the heart of the region, from Strasbourg to Colmar, with stops in Obernai and Riquewihr. The air is infused with the delightful aroma of local wines—a real feast for the senses. As you travel eastward, you’ll cross the Rhine River toward the majestic Breisach am Rhein. Not far off, discover the vibrant university city of Freiburg im Breisgau, boasting a lively market square and other attractions.
Continue your journey on the renowned Route 500 through the enchanting Black Forest, leading you to the charming spa town of Baden-Baden. On your return to Frankfurt am Main, make sure to explore Heidelberg and its awe-inspiring castle. Frankfurt, a city rich in museums, culture, music, history, and gardens, offers a diverse range of attractions. Plan two to three days to fully appreciate its wealth of offerings, including a visit to the historic old town and the opportunity to ascend the Main Tower for panoramic views. Don’t forget to explore the bustling central shopping street, Zeil.
Popular itinerary From Mainz to Frankfurt am Main with a Focus on Wine and Cuisine:
Here is the detailed proposed itinerary:
Day 1: From Frankfurt am Main through Mainz to Speyer
From the Frankfurt am Main airport, travel on Roads 3, 66, and 355 for about 18 miles to Mainz, situated on the banks of the Rhine River. Mainz is a city where history, culture, and modernity converge. In the center of the old town stands the Mainz Cathedral, a masterpiece of Romanesque architecture. Adjacent to the cathedral, the Gutenberg Museum provides a broad platform for the inventor of the printing press, showcasing ancient manuscripts and the world’s first printed Bible.
In the old town, you’ll see charming squares, medieval timber-framed houses, and a bustling market. The Kirschgarten is one of the oldest squares in Germany, with medieval charm and inviting cafes. St. Stephen’s Church boasts magnificent stained glass windows designed by the artist Marc Chagall, illustrating scenes from the Old Testament. These elaborate works of art are best appreciated in daylight, particularly during the winter months.
From Mainz, head 62 miles along Roads 63 and 61 towards the city of Speyer. The heart of Speyer’s old town is dominated by its impressive cathedral, a UNESCO World Heritage site, and one of Germany’s most important Romanesque buildings. This awe-inspiring cathedral, marked by its impressive architecture and centuries-old legacy, attests to the city’s religious and cultural importance. A bustling shopping street, lined with an array of shops, restaurants, cafes, and stalls, extends from the cathedral to the city gate. Additionally, one of Europe’s most remarkable aviation and space museums, Technik Museum, is located here, featuring diverse exhibitions ranging from vintage cars, motorcycles, and airplanes to carts and even space capsules.
Spend the night in Speyer.
Day 2: From Speyer through Wissembourg to Strasbourg
Today’s approximately 93-mile route begins on the German Wine Road. Travel to the charming town of Neustadt an der Weinstrasse, located about 18 miles from Speyer along Road 39. Don’t miss the opportunity to visit Hambach Castle for a magnificent view and a tour of the local heritage museum. Among the exhibits is the black, red, and gold German flag, which was first raised here at the festival held in 1832.
As you continue south, explore the roads parallel to Route 65 to discover charming local wine villages. In Landau, the main town along the Wine Route, you’ll find an outstanding museum called Reptilium Terrarien- und Wüstenzoo GmbH. This museum is dedicated to reptiles and features a diverse collection of reptiles, amphibians, and desert animals. The exhibits are housed in enclosures designed to replicate their natural habitats.
The next destination is Bad Bergzabern, where you can immerse yourself in the medieval ambiance. A must-visit is the remarkable 16th-century building, Gasthaus Zum Engel, located on Konigstrasse Street.
A short drive on Road 38 will bring you to the charming town of Schweigen Rechtenbach. It’s recommended to park near the “Wine Gate,” known as Deutschen Weintor, and take a walking tour focusing on vine cultivation. This guided tour, named Weinlehrpfades, provides informational stations, and you’ll find a map at the starting point. Explore a variety of Palatinate wines in the area, including Neustadt Classic, Dornfelder, Grauburgunder, Spätburgunder, and Scheurebe.
Continuing your journey, you’ll cross into the French Alsace region and arrive in the picturesque town of Wissembourg. This town holds historical significance as the site of the first battle in the 1870 war, during which the German army advanced to the gates of Paris and annexed the Alsace region. From Wissembourg, proceed to the city of Strasbourg.
Spend the night in Strasbourg.
Day 3: Strasbourg
Start exploring the city at the Place de la République square. From there, proceed to the magnificent cathedral, adorned with Gothic details, particularly notable for its stunning stained glass windows featuring the iconic “Rose,” a symbol of the city. Inside the cathedral, don’t miss the opportunity to observe the famous Astronomical Clock. Moving on from the cathedral, head to Place Gutenberg, named after Johannes Gutenberg, the inventor of the printing press. Continue to the central square, Place Kléber, surrounded by architectural gems, including the Aubette Palace and other elegant buildings.
Wind through the narrow streets of the old town to the charming district of La Petite France, known for its picturesque alleys and ancient houses. On its outskirts, you’ll see Barrage Vauban, a 17th-century dam with a breathtaking view. Cross the dam to the opposite bank, where a unique blend of medieval and Renaissance architecture awaits. On your way back, pass through Place Broglie, another central square surrounded by notable buildings. Cross Rue des Hallebardes, a lively street lined with shops and cafes, and, if time allows, consider a visit to the Strasbourg Museum of Modern and Contemporary Art (MAMCS).
Strasbourg is renowned for its foie gras, especially in the form of pâté. This delicacy, made from duck or goose liver, is typically served with crusty bread.
Spend the night in Strasbourg.
Day 4: From Strasbourg to Colmar on the Alsace Wine Route
Today’s journey is through the delightful Alsace region, covering around 80 miles along roads that wind through the magnificent wine areas between Strasbourg and Colmar. There are several routes, and it is recommended to choose internal roads such as Route 35-D or 18-D to fully enjoy the scenic wine region rich in vineyards, orchards, and small villages. Here are some recommended stopping points:
Obernai is a charming and picturesque town that embodies the distinct Alsatian charm with its cobblestone streets and flower-adorned timber-framed houses set against the backdrop of vineyards and orchards. The town is known for its well-preserved medieval architecture, including the St. Pierre and St. Paul Churches.
Château du Haut-Kœnigsbourg is a medieval fortress with a rich history dating back to the 12th century, providing sweeping views of the Alsace plains and the Vosges Mountains. The castle features military architecture and well-preserved living quarters, including a drawbridge, turrets, and a magnificent hall, which are symbols of medieval heritage.
Ribeauvillé is a picturesque town nestled among hills covered with vineyards, known for its well-preserved medieval architecture. Surrounded by vineyards, it is situated in the heart of the wine region.
Riquewihr, a charming town famous for its well-preserved timber-framed houses, cobblestone streets, and colorful facades, is a popular tourist destination, hosting events and festivals throughout the year, including the renowned Christmas market.
Along the wine route, you’ll come across various local wines such as Riesling, Gewürztraminer, Pinot Gris, Pinot Noir, Muscat, Sylvaner, and Crémant d’Alsace.
Spend the night in Colmar.
Day 5: Colmar
The streets of the charming old town of Colmar are lined with timber-framed houses, cobblestone streets, and beautiful squares. The Maison Pfister, a 16th-century house adorned with ornate wooden carvings, and the Maison des Têtes, known for its sculpted heads, are examples of the city’s medieval charm. The Saint-Martin Collegiate Church, a remarkable Gothic masterpiece with a soaring spire offering panoramic views of the city, is located in the historic quarter.
The town’s picturesque canals, lined with colorful houses and beautiful flowers, earned Colmar the endearing moniker “Little Venice.” A boat ride along the Lauch River provides a unique perspective, allowing visitors to marvel at the town from a distinctive vantage point and soak in its romantic atmosphere. The Unterlinden Museum is housed in a former Dominican monastery and contains art masterpieces.
Colmar offers a delightful taste of Alsatian cuisine, featuring local specialties such as flammekueche (local pizza), choucroute garnie (sauerkraut with sausages and meats), and traditional cakes or cookies like “kugelhopf” and Tarte flambée.
Spend the night in Colmar.
Day 6: From Colmar through Breisach am Rhein to Freiburg im Breisgau
Travel this morning along Route 415D for approximately 15.5 miles to reach the town of Breisach am Rhein, a charming and historic city situated on the banks of the Rhine River. St. Stephen’s Cathedral stands proudly on the skyline, showcasing a blend of Romanesque and Gothic architecture. From the cathedral’s terrace, there is a spectacular view of the wine region, known as Kaiserstuhl.
The town’s streets lead to well-preserved medieval buildings, and, along the slopes of the cathedral, there are inviting boutiques, cafes, restaurants, and, of course, a variety of wines from the region’s vineyards.
From Breisach, follow Routes 415D and 5 to reach Freiburg im Breisgau, a city that blends medieval charm with modern structures. Explore the delightful old town, characterized by the iconic cathedral, where medieval architecture, meandering streets, and vibrant markets offer a journey through time. The city’s uniqueness is enhanced by a network of narrow water channels known as Bächle that flow through the cobblestone streets. The old and new town halls, exemplifying Gothic and Renaissance architecture, stand as masterpieces reflecting the city’s rich history.
At Munstermarkt, the lively market square in front of the cathedral, locals and tourists have gathered for centuries. It’s recommended to check the market’s opening hours in advance. This bustling square is also the perfect spot to savor a local delicacy – sausages served with sauerkraut and bread.
Spend the night in Freiburg im Breisgau.
Day 7: From Freiburg im Breisgau to Baden-Baden
Drive along Routes 5 and 86L for approximately 93 miles until you reach the renowned Black Forest High Road (500). When you reach the junction with Road 500, head south toward Lake Mummelsee, a stunning glacial lake and one of the region’s famous natural attractions. The tranquil lake is surrounded by dense forests and rolling hills, steeped in folklore and local legends. After parking your car, enjoy a brief stroll to the enchanting lake before heading north again on the winding and picturesque Road 500 towards the spa town of Baden-Baden.
Baden-Baden presents a delightful fusion of luxurious spa facilities, cultural richness, and sophistication. The thermal baths and spas create an oasis for relaxation and renewal, inviting guests to indulge in the therapeutic waters that have attracted visitors for centuries. The city’s architectural grandeur is showcased in the splendid Kurhaus, a masterpiece housing a casino and concert hall.
Beyond its contemporary allure, Baden-Baden takes pride in its Roman spa town legacy. The Roman baths, dating back to the 1st century AD, offer a glimpse into the ancient thermal traditions. The Friedrichsbad, originating from the Roman period, has been pampering guests since the 19th century. Don’t miss Trinkhalle, a neo-classical drinking hall built in the 19th century that was once used as a source for various types of mineral-rich drinking water. Its magnificent architecture and spacious surroundings add an air of elegance to the area.
Spend the night in Baden-Baden.
Day 8: From Baden-Baden through Heidelberg to Frankfurt am Main
Start the day on Highway 5, covering a distance of about 56 miles to reach the university town of Heidelberg, located on the banks of the Neckar River. This picturesque town provides one of the most stunning panoramic views in the area. Heidelberg boasts a history steeped in significant events, attracting princes and electors who constructed remarkable structures, including the iconic Heidelberg Castle, proudly perched above the city overlooking the twists of the river and its unique houses.
Throughout its 500-year history, Heidelberg Castle has undergone numerous transformations until its demise at the hands of Louis XIV’s army in the 17th century. Explore the wine cellar featuring colossal wooden barrels, ascend the wooden staircase leading to the massive vat with a capacity of approximately 220,000 liters. Upon descending from the vat, you’ll encounter the courtyard jester, Perkeo. Be sure to visit the panoramic viewpoint with awe-inspiring views. From the inner courtyard, you can visit the German Pharmacy Museum, a fascinating exhibition showcasing an extraordinary collection of containers, instruments, raw materials, and processing tools used in the past for preparing medicines.
Heidelberg University, founded in 1386 with papal support, is the oldest university in Germany. It has gained renown for its research capabilities, esteemed medical faculty, and the impressive Universitatbibliothek library, home to millions of manuscripts and books, some of which date back many centuries. Visitors can enter the university and the ancient library on Plock Street 107.
The historic center, Marktplatz square, the Church of the Holy Spirit, and the surrounding areas offer an ideal setting for leisurely strolls amid shops and city houses.
Heading towards the river, the old bridge constructed in 1788, with its distinct helmet-shaped towers reminiscent of Persian helmets, is a notable tourist attraction. The western tower once housed punishment chambers for offenders. Before ascending the bridge for a stunning view of the castle, you’ll see a statue of a cheerful monkey holding a mirror. What’s the message? It’s up for individual interpretation…
At the end of the day, travel approximately 56 miles on Highway 5 to reach the city of Frankfurt am Main.
Days 9 and 10: Frankfurt am Main
Frankfurt am Main boasts a plethora of attractions, making it advisable to allocate two to three days for your visit. Primarily known as Germany’s financial hub, the city is centered around the Frankfurt Stock Exchange, established in 1585, and is surrounded by towering skyscrapers, earning it the moniker “Mainhattan.” The historic and compact city center is easily navigable on foot.
Start the tour at the train station and proceed along Kaiserstrasse or one of its parallel streets towards the skyscraper skyline. At Neue Mainzer Strasse 52, the Main Tower offers the option to ascend (for a fee) to the top for a magnificent view of the city and its surroundings. Continuing from Main Tower towards Grosser Hirschgraben 21, you’ll find the residence of the writer, poet, playwright, and polymath Johann Wolfgang von Goethe.
A short walk from Goethe’s residence leads to the Protestant Paulskirche, a round-shaped church, and from there, a brief stroll will lead to the heart of the old town and the Römer, the city hall. Romerberg, the central square near the Justice statue, provides a full view of the meticulously reconstructed city hall with its neo-Gothic façade. The original building was erected in the early 15th century, and all existing structures today were faithfully restored over the course of many years.
For those interested in iconography, a highly recommended visit is to the Icons Museum (Ikonenmuseum), showcasing a quality and extensive collection in the field. This is just one of several quality museums located near the old town. The Old Bridge of Frankfurt crosses the Main River, and the museums are within a short walking distance on the opposite bank.
The impressive Frankfurt Opera House is slightly off the walking path and is located near the city’s green belt, accessible by public transportation. Along the shopping street Zeil, close to the old town, you’ll find a wide selection of boutiques, shops, restaurants, and cafes.
Known also for its cuisine, Frankfurt offers a diverse array of local delicacies, including:
Frankfurter Würstchen: Small and thin smoked pork sausages traditionally served with mustard and fresh buns.
Handkäse mit Musik: Sour milk cheese marinated with onions, caraway seeds, and sometimes vinegar, usually served with bread.
Rippchen mit Kraut: Grilled pork knuckles served with pickled cabbage and potatoes – a hearty and satisfying meal.
Frankfurter Rindswurst: Smoked beef sausage typically served with mustard and bread.
